Signaling Pathways in Osteoclast Differentiation
نویسندگان
چکیده
منابع مشابه
Signaling Pathways in Osteoclast Differentiation
Osteoclasts are multinucleated cells of hematopoietic origin that are responsible for the degradation of old bone matrix. Osteoclast differentiation and activity are controlled by two essential cytokines, macrophage colony-stimulating factor (M-CSF) and the receptor activator of nuclear factor-κB ligand (RANKL). M-CSF and RANKL bind to their respective receptors c-Fms and RANK to stimulate oste...
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ژورنال
عنوان ژورنال: Chonnam Medical Journal
سال: 2016
ISSN: 2233-7385,2233-7393
DOI: 10.4068/cmj.2016.52.1.12